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dc.contributor.authorAdam, Jamila Khatoon
dc.contributor.authorDyer, Robby B.
dc.contributor.authorHarrypaul, Ashika
dc.contributor.authorRmaih, Wafaa
dc.date.accessioned2012-12-05T08:01:19Z
dc.date.available2012-12-05T08:01:19Z
dc.date.issued2012
dc.identifier.citationJamila Khatoon Adam, Robby Dyer, Ashika Harrypaul, Wafaa Rmaih. "Two year clinical outcomes after sirolimus-eluting stent implantation for the treatment of coronary artery disease". Medical Technology SA. Vol. 26, no. 1 (2012): 18-21en_US
dc.identifier.issn1011 5528
dc.identifier.urihttp://hdl.handle.net/10321/789
dc.description.abstractBackground Coronary artery stents are known to reduce rates of restenosis after coronary stenting, but it is uncertain how long this benefit is maintained. Clinical data has raised concerns that drug-eluting stents are associated with increased rates of late stent thrombosis, death or myocardial infarction. Objectives To evaluate the safety and reliability of sirolimus-eluting stents in real-world practice out to two years. Methods From January 2008 to June 2008, 30 patients were enrolled in the study after implantation of one or more sirolimus-eluting stents. We evaluated clinical follow-up information for up to two years after the implantation of Cypher® Select stents in 30 patients with 35 lesions. Results Mean patient age was 62.33 +/- 10.99 years, 7 percent were diabetic and 30 percent presented with acute myocardial infarctions. The procedure’s success rate was 100 percent for the sirolimus-eluting stent implantation, and follow-up rates were 100 percent. Mean total stent length was 22.32 +/- 6.63 mm, with 13 percent receiving more than one stent. Two year freedom from mortality, myocardial infarction, target vessel revascularization and stent thrombosis was 100 percent. Dual antiplatelet therapy was taken by 100 percent at 1 month, 53 percent at 6 months, 40 percent at 1 year and 0 percent of patients at 2 years. The rate of survival free of myocardial infarction, bypass surgery and repeated angioplasty for stented lesions was 100% at two years. Conclusions Treatment of lesions with sirolimus-eluting stents is associated with a sustained clinical benefit two years after device implantation.en_US
dc.format.extent6 pen_US
dc.language.isoenen_US
dc.publisherMedical Technology SAen_US
dc.rightsThis work is licensed under a Creative Commons Attribution License.en_US
dc.subjectCoronary artery diseaseen_US
dc.subjectSerolimus-eluting stentsen_US
dc.subjectCypher selecten_US
dc.subject.lcshCoronary arteries--Stenosisen_US
dc.subject.lcshStents (Surgery)en_US
dc.titleTwo year clinical outcomes after sirolimus-eluting stent implantation for the treatment of coronary artery diseaseen_US
dc.typeArticleen_US
dc.dut-rims.pubnumDUT-001613


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