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Two year clinical outcomes after sirolimus-eluting stent implantation for the treatment of coronary artery disease

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dc.contributor.author Adam, Jamila Khatoon
dc.contributor.author Dyer, Robby B.
dc.contributor.author Harrypaul, Ashika
dc.contributor.author Rmaih, Wafaa
dc.date.accessioned 2012-12-05T08:01:19Z
dc.date.available 2012-12-05T08:01:19Z
dc.date.issued 2012
dc.identifier.citation Jamila Khatoon Adam, Robby Dyer, Ashika Harrypaul, Wafaa Rmaih. "Two year clinical outcomes after sirolimus-eluting stent implantation for the treatment of coronary artery disease". Medical Technology SA. Vol. 26, no. 1 (2012): 18-21 en_US
dc.identifier.issn 1011 5528
dc.identifier.uri http://hdl.handle.net/10321/789
dc.description.abstract Background Coronary artery stents are known to reduce rates of restenosis after coronary stenting, but it is uncertain how long this benefit is maintained. Clinical data has raised concerns that drug-eluting stents are associated with increased rates of late stent thrombosis, death or myocardial infarction. Objectives To evaluate the safety and reliability of sirolimus-eluting stents in real-world practice out to two years. Methods From January 2008 to June 2008, 30 patients were enrolled in the study after implantation of one or more sirolimus-eluting stents. We evaluated clinical follow-up information for up to two years after the implantation of Cypher® Select stents in 30 patients with 35 lesions. Results Mean patient age was 62.33 +/- 10.99 years, 7 percent were diabetic and 30 percent presented with acute myocardial infarctions. The procedure’s success rate was 100 percent for the sirolimus-eluting stent implantation, and follow-up rates were 100 percent. Mean total stent length was 22.32 +/- 6.63 mm, with 13 percent receiving more than one stent. Two year freedom from mortality, myocardial infarction, target vessel revascularization and stent thrombosis was 100 percent. Dual antiplatelet therapy was taken by 100 percent at 1 month, 53 percent at 6 months, 40 percent at 1 year and 0 percent of patients at 2 years. The rate of survival free of myocardial infarction, bypass surgery and repeated angioplasty for stented lesions was 100% at two years. Conclusions Treatment of lesions with sirolimus-eluting stents is associated with a sustained clinical benefit two years after device implantation. en_US
dc.format.extent 6 p en_US
dc.language.iso en en_US
dc.publisher Medical Technology SA en_US
dc.rights This work is licensed under a Creative Commons Attribution License. en_US
dc.subject Coronary artery disease en_US
dc.subject Serolimus-eluting stents en_US
dc.subject Cypher select en_US
dc.subject.lcsh Coronary arteries--Stenosis en_US
dc.subject.lcsh Stents (Surgery) en_US
dc.title Two year clinical outcomes after sirolimus-eluting stent implantation for the treatment of coronary artery disease en_US
dc.type Article en_US
dc.dut-rims.pubnum DUT-001613


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