Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/2461
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dc.contributor.authorSingh, Gulshanen_US
dc.contributor.authorVajpayee, Poornimaen_US
dc.contributor.authorRani, Neetikaen_US
dc.contributor.authorAmoah, Isaac Dennisen_US
dc.contributor.authorStenström, Thor-Axelen_US
dc.contributor.authorShanker, Rishien_US
dc.date.accessioned2017-06-14T14:28:43Z-
dc.date.available2017-06-14T14:28:43Z-
dc.date.issued2016-
dc.identifier.citationSingh, G. et al. 2016. Exploring the potential reservoirs of non specific TEM beta lactamase (blaTEM) gene in the Indo-Gangetic region : a risk assessment approach to predict health hazards. Journal of Hazardous Materials. 314: 121-128.en_US
dc.identifier.issn0304-3894 (print)-
dc.identifier.issn1873-3336 (online)-
dc.identifier.urihttp://hdl.handle.net/10321/2461-
dc.description.abstractThe emergence of antimicrobial resistant bacteria is an important public health and environ-mental contamination issue. Antimicrobials of -lactam group accounts for approximately two thirds, by weight, of all antimicrobials administered to humans due to high clinical efficacy and low toxicity. This study explores -lactam resistance determinant gene (blaTEM) as emerging con-taminant in Indo-Gangetic region using qPCR in molecular beacon format. Quantitative Microbial Risk Assessment (QMRA) approach was adopted to predict risk to human health associated with consumption/exposure of surface water, potable water and street foods contaminated with bac-teria having blaTEM gene. It was observed that surface water and sediments of the river Ganga and Gomti showed high numbers of blaTEM gene copies and varied significantly (p < 0.05) among the sampling locations. The potable water collected from drinking water facility and clinical set-tings exhibit significant number of blaTEM gene copies (13 ± 0.44–10200 ± 316 gene copies/100 mL).en_US
dc.format.extent8 pen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of hazardous materials (Online)en_US
dc.subjectEnvironmental reservoirsen_US
dc.subjectblaTEM geneen_US
dc.subjectMolecular beaconen_US
dc.subjectQuantitative PCRen_US
dc.subjectβ-lactamase resistanceen_US
dc.titleExploring the potential reservoirs of non specific TEM beta lactamase (blaTEM) gene in the Indo-Gangetic region : a risk assessment approach to predict health hazardsen_US
dc.typeArticleen_US
dc.dut-rims.pubnumDUT-005668en_US
dc.description.availabilityCopyright: 2016. Elsevier. Due to copyright restrictions, only the abstract is available. For access to the full text item, please consult the publisher's website. The definitive version of the work is published in Journal of Hazardous Materials, Vol 314. Pp 121-128. https://www.ncbi.nlm.nih.gov/pubmed/27111425en_US
dc.identifier.doi10.1016/j.jhazmat.2016.04.036-
local.sdgSDG06-
local.sdgSDG03-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.fulltextNo Fulltext-
Appears in Collections:Research Publications (Academic Support)
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