Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/4737
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dc.contributor.authorNaidoo, Levanien_US
dc.contributor.authorReddy, Poovendhreeen_US
dc.date.accessioned2023-04-26T09:18:02Z-
dc.date.available2023-04-26T09:18:02Z-
dc.date.issued2022-12-
dc.identifier.citationNaidoo, L. and Reddy, P. 2022. Stakeholder knowledge and attitudes toward the use of predictive genetic testing in South Africa. Journal of Community Genetics. 13(6): 567-577. doi:10.1007/s12687-022-00606-yen_US
dc.identifier.issn1868-310X-
dc.identifier.issn1868-6001 (Online)-
dc.identifier.otherisidoc: 6I9UN-
dc.identifier.otherpubmed: 36085342-
dc.identifier.urihttps://hdl.handle.net/10321/4737-
dc.description.abstractThe use of predictive genetic testing, particularly for risk profiling in non-communicable diseases (NCDs), has the potential to benefit public health by decreasing the disease burden and alleviating the pressure on healthcare. It is thus important to assess knowledge and uptake among stakeholders. This study aimed to assess end users' (community, medical practitioners and medical students) knowledge and attitudes regarding the use and support of genomic medicine. A descriptive cross-sectional survey was conducted in Kwazulu-Natal (KZN) among 3 groups of stakeholders (nā€‰=ā€‰170): medical practitioners from both private and public healthcare, medical students from UKZN and community members represented by teachers. Three structured questionnaires using a Likert scale were administered. Responses were stratified by practice type, and a scoring scale was developed. Principal component analysis (PCA) was used to reduce data on all constructs that made up each variable. All three groups showed adequate knowledge and a positive attitude towards use, apart from medical students who were not as keen to support future use in their own practice. Although medical practitioners supported the use of this technology, with necessary guidelines, expertise and affordability, only 18% from private practice reported having used it. PCA reduced data to fewer parsimonious constructs for all 3 groups: common threads included an awareness that genetic testing may improve health and disease outcomes; guidelines for use; and the provision of education to increase awareness, training to bolster expertise and confidence to use these services. Participants in this study attributed a lack of uptake to limited expertise and professional support, and a lack of legislative guidelines. We recommend updating continuing professional development for medical practitioners and promoting community education concomitantly. Provision of guidelines and increased accessibility to resources are important.en_US
dc.format.extent11 pen_US
dc.format.mediumPrint-Electronic-
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media LLCen_US
dc.relation.ispartofJournal of Community Genetics; Vol. 13, Issue 6en_US
dc.subjectGenomic medicinesen_US
dc.subjectDisease risken_US
dc.subjectGenetic testingen_US
dc.subjectNCDsen_US
dc.subjectPCAen_US
dc.subjectDisease risken_US
dc.subjectGenetic testingen_US
dc.subjectGenomic medicinesen_US
dc.subjectNCDsen_US
dc.subjectPCAen_US
dc.subject0604 Geneticsen_US
dc.titleStakeholder knowledge and attitudes toward the use of predictive genetic testing in South Africaen_US
dc.typeArticleen_US
dc.date.updated2023-04-13T08:51:12Z-
dcterms.dateAccepted2022-8-30-
dc.identifier.doi10.1007/s12687-022-00606-y-
local.sdgSDG03-
local.sdgSDG17-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.fulltextWith Fulltext-
Appears in Collections:Research Publications (Health Sciences)
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