Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/5059
DC FieldValueLanguage
dc.contributor.authorGuru Prasad, V.en_US
dc.contributor.authorKuruvalli, Gouthamien_US
dc.contributor.authorLavanya, L.en_US
dc.contributor.authorKrishna, Suresh Babu Naiduen_US
dc.contributor.authorImran, Khaliden_US
dc.contributor.authorReddy, Vaddi Damodaraen_US
dc.date.accessioned2023-11-09T09:29:01Z-
dc.date.available2023-11-09T09:29:01Z-
dc.date.issued2023-10-05-
dc.identifier.citationGuru Prasad, et al. 2023. Studies on phytochemical screening, GC-MSanalysis and their antibacterial property against Vibrio cholerae. Current Trends in Biotechnology and Pharmacy. 17(3s): 1079-1089. doi:10.5530/ctbp.2023.3s.46en_US
dc.identifier.issn0973-8916-
dc.identifier.issn2230-7303 (Online)-
dc.identifier.urihttps://hdl.handle.net/10321/5059-
dc.description.abstractIn the current study, two different MTCC strains of Vibrio cholera, 3904 and 3906, were used to determine the anti-bacterial properties of Cinnamomum verum (C. verum) leaves (Family: Lauraceae). This was done through qualitative phytochemical compound screening and quantitative identification of volatile compounds using gas chromatography and mass spectrometry (GC-MS). Methanolic extract was subjected to phytochemical screening in order to determine the active components. Through qualitative examination revealed that the substance contained alkaloids, total carbohydrates, cardiac glycosides, flavonoids, glycosides, phenols, saponins, and tannins. Due to the abundance of phytochemical agents in the extract, GC-MS experiments were conducted. Based on their retention times and coverage percentages in mass spectra, these studies identified 42 volatile chemicals. The maximum zone of inhibition for the antibacterial activity of methanol extract were 15.9 mm for the V. cholera MTCC 3904 strain and 16.3 mm for the V. cholera MTCC 3906 strain, respectively, at concentrations of 100μL, Azithromycin showed 22.30 mm, a positive control, at a dosage of 30μg. Total antibacterial activity was determined to be 15.05 ±1.15 mm and 15.10±1.15 mm, respectively, in the examined bacterial strains. These values are equivalent to conventional azithromycin. In conclusion, C. verum can be a potential therapeutic agent against V. cholera strains, this is due to strong antibacterial nature of active biomolecules present in the medicinal plant.en_US
dc.format.extent11 pen_US
dc.language.isoenen_US
dc.relation.ispartofCurrent Trends in Biotechnology and Pharmacy; Vol. 17, Issue 3sen_US
dc.subject11 Medical and Health Sciencesen_US
dc.subjectCinnamomum verumen_US
dc.subjectPhytochemicalsen_US
dc.subjectGC-MS analysisen_US
dc.subjectV. choleraen_US
dc.subjectAzithromycen_US
dc.titleStudies on phytochemical screening, GC-MS analysis and their antibacterial property against Vibrio choleraeen_US
dc.typeArticleen_US
dc.date.updated2023-10-31T09:33:41Z-
dc.identifier.doi10.5530/ctbp.2023.3s.46-
local.sdgSDG03-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.fulltextWith Fulltext-
Appears in Collections:Research Publications (Applied Sciences)
Files in This Item:
File Description SizeFormat
Curr Tre in Bio Pha Copyright Clearance.docxCopyright clearance156.99 kBMicrosoft Word XMLView/Open
Guru Prasad et al_2023.pdfArticle2.79 MBAdobe PDFView/Open
Show simple item record

Page view(s)

273
checked on Dec 22, 2024

Download(s)

77
checked on Dec 22, 2024

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.