Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/5664
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dc.contributor.authorUmarsingh, Shalinien_US
dc.contributor.authorAdam, Jamila Khatoonen_US
dc.contributor.authorKrishna, Suresh Babu Naiduen_US
dc.date.accessioned2024-11-22T18:08:26Z-
dc.date.available2024-11-22T18:08:26Z-
dc.date.issued2020-12-22-
dc.identifier.citationUmarsingh, S., Adam, J.K. and Krishna, S.B.N. 2020. The relationship between anti-Mullerian hormone (AMH) levels and pregnancy outcomes in patients undergoing assisted reproductive techniques (ART). PEERJ. 8: 1-14. doi:10.7717/peerj.10390en_US
dc.identifier.issn2167-8359 (Online)-
dc.identifier.otherisidoc: PI1BD-
dc.identifier.otherpubmed: 33391866-
dc.identifier.urihttps://hdl.handle.net/10321/5664-
dc.description.abstractA variety of predictors are available for ovarian stimulation cycles in assisted reproductive technology (ART) forecasting ovarian response and reproductive outcome in women including biomarkers such as anti- Müllerian hormone (AMH). The aim of our present study was to compare the relationship between AMH levels and pregnancy outcomes in patients undergoing intra-cytoplasmic sperm injection (ICSI). Overall, fifty patients (<i>n</i> = 50), aged 20-45 years were recruited for the present prospective study. Three AMH levels were presented with high often poly cystic ovarian syndrome (PCOS) amongst 52.4% patients, 40.5% in normal and 7.1% in low to normal, correspondingly. There was statistically significant relationship between AMH and day of embryo transfer (<i>p</i> < 0.05). The Pearson analysis between AMH, age, E2 and FSH displayed no statistically significant relationship between E2 and AMH (<i>p</i> < 0.05) and negative correlation between FSH and age (<i>p</i> > 0.05). The area under the receiver operating characteristic curve for E<sub>2</sub> was 0.725 and for AMH levels as predictors of CPR was 0.497 indicating E<sub>2</sub> as better predictor than AMH. The number of oocytes, mature oocytes and fertilized oocytes all presented a weak positive relationship to AMH. Our results confirm the clinical significance of AMH to accurately predict ovarian reserve as a marker and its limitations to use as predictor for a positive pregnancy outcome. Additional prospective studies should be conducted to validate the predictive capability of AMH levels for the outcome of clinical pregnancy.en_US
dc.format.extent14 pen_US
dc.format.mediumElectronic-eCollection-
dc.language.isoenen_US
dc.publisherPeerJen_US
dc.relation.ispartofPEERJ; Vol. 8en_US
dc.subjectAnti-Mullerian hormoneen_US
dc.subjectFertilization in vitroen_US
dc.subjectPregnancyen_US
dc.subjectEnzyme-linked immunosorbent assayen_US
dc.subjectOocytesen_US
dc.subjectClinical pregnancy rateen_US
dc.subjectAnti-Müllerian hormoneen_US
dc.subjectClinical pregnancy rateen_US
dc.subjectEnzyme-linked immunosorbent assayen_US
dc.subjectFertilization in vitroen_US
dc.subjectOocytesen_US
dc.subjectPregnancyen_US
dc.subject06 Biological Sciencesen_US
dc.subject11 Medical and Health Sciencesen_US
dc.titleThe relationship between anti-Mullerian hormone (AMH) levels and pregnancy outcomes in patients undergoing assisted reproductive techniques (ART)en_US
dc.typeArticleen_US
dc.date.updated2024-11-18T12:02:11Z-
dc.publisher.urihttp://dx.doi.org/10.7717/peerj.10390en_US
dcterms.dateAccepted2020-10-27-
dc.identifier.doi10.7717/peerj.10390-
item.grantfulltextopen-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.openairetypeArticle-
Appears in Collections:Research Publications (Health Sciences)
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