Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/1178
DC FieldValueLanguage
dc.contributor.authorJinabhai, Champaklal C.en_US
dc.contributor.authorTathiah, Nerishaen_US
dc.contributor.authorParboosing, Raveenen_US
dc.contributor.authorSingh, Lavanyaen_US
dc.contributor.authorMoodley, Pravien_US
dc.date.accessioned2015-01-14T12:44:13Z-
dc.date.available2015-01-14T12:44:13Z-
dc.date.issued2013-08-22-
dc.identifier.citationTathiah, N.; Parboosing, R.; Singh, L.; Jinabhai, C.C. and Moodley, P. 2014. Human immunodeficiency virus and hepatitis B or C co-infection in KwaZulu-Natal: a retrospective analysis of a laboratory database. Southern African Journal of Infectious Diseases;29(1):19-22en_US
dc.identifier.issn1015-8722-
dc.identifier.urihttp://hdl.handle.net/10321/1178-
dc.description.abstractHepatitis B or C virus infection has an important influence on treatment and outcomes in human immunodeficiency virus (HIV)-infected individuals. HIV worsens the prognosis in hepatitis B- or C virus-infected patients, and patients on antiretroviral therapy are more likely to experience hepatotoxicity if they are co-infected with a hepatotropic virus. There is a paucity of data on the epidemiology of hepatotropic viruses in relation to each other and to HIV in KwaZulu-Natal. The aim of this study was to describe the seroprevalence of hepatitis B and C virus in HIV-positive and -negative individuals in KwaZulu-Natal from 2002-2010, using a large laboratory database of routine serological results. Patients who had an HIV or hepatitis B or C test performed at the National Health Laboratory Service Department of Virology in Durban from 2002-2010 were included in the study. The study revealed that the overall seropositivity of hepatitis B surface antigen (HBsAg) was 12.05%, and that of hepatitis C immunoglobulin G (IgG), 4.13%. Individuals who were seropositive for HIV had 3.19-fold increased odds of being positive for HBsAg, 2.06-fold increased odds of being hepatitis B virus e antigen-positive, and 2.91-fold increased odds of being hepatitis C virus IgG-positive. Of those individuals who were tested for HBsAg and hepatitis C virus IgG (irrespective of HIV status), 15.76% were seropositive for both markers. HIV-positive individuals are at increased odds of having markers for hepatitis B and C infection.en_US
dc.format.extent4 pen_US
dc.language.isoenen_US
dc.publisherSAJEIen_US
dc.relation.ispartofCorporate ownership & control (CD-ROM)en_US
dc.subjectHepatitisen_US
dc.subjectHIVen_US
dc.subjectHepatitis Ben_US
dc.subjectHepatitis Cen_US
dc.subjectCo-infectionen_US
dc.subjectSouth Africaen_US
dc.titleHuman immunodeficiency virus and hepatitis B or C co-infection in KwaZulu-Natal: a retrospective analysis of a laboratory databaseen_US
dc.typeArticleen_US
dc.publisher.urihttp://www.sajei.co.za/index.php/SAJEI/article/view/560en_US
dc.dut-rims.pubnumDUT-004339en_US
dc.identifier.doi10.1080/23120053.2014.11441561-
local.sdgSDG03-
item.languageiso639-1en-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.grantfulltextopen-
Appears in Collections:Research Publications (Health Sciences)
Files in This Item:
File Description SizeFormat
jinabhai_et_al_2014.pdf170.38 kBAdobe PDFThumbnail
View/Open
Show simple item record

Page view(s)

661
checked on Dec 13, 2024

Download(s)

282
checked on Dec 13, 2024

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.