Please use this identifier to cite or link to this item: https://hdl.handle.net/10321/2884
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dc.contributor.advisorBhoola, K. D.-
dc.contributor.authorMoodley, Rumeshaen_US
dc.date.accessioned2017-11-15T08:17:58Z
dc.date.available2017-11-15T08:17:58Z
dc.date.issued2003-
dc.identifier.other70758-
dc.identifier.urihttp://hdl.handle.net/10321/2884-
dc.descriptionSubmitted in part fulfilment for the Degree of Master of Technology: Biotechnology, Durban Institute of Technology, Durban, South Africa, 2003.en_US
dc.description.abstractEvidence suggests that the induction of tissue kallikrein, and the subsequently formed kinins, enhances proliferation of tumour cells because of their mitogenic property. Additionally, the kinin peptides are believed to promote the invasion of normal tissue by tumour cells. TGF-l is a potent inhibitor of the growth of renal epithelial cells, and is a classical anti-mitogen, which is central to many of its antiproliferative effects. No studies thus far have been performed, as to whether the proposed anti-mitogenesis ofTGF-1 has a regulatory effect on the cell proliferative action of kinins on renal epithelial and carcinoma cells.en_US
dc.format.extent141 pen_US
dc.language.isoenen_US
dc.subject.lcshTransforming growth factors-betaen_US
dc.subject.lcshKallikreinen_US
dc.subject.lcshImmunopharmacologyen_US
dc.subject.lcshCancer--Immunotherapyen_US
dc.titleThe co-localization of tissue kallikrein and transforming growth factor - beta 1 in the non-cancerous and cancerous kidneyen_US
dc.typeThesisen_US
dc.description.levelMen_US
dc.identifier.doihttps://doi.org/10.51415/10321/2884-
local.sdgSDG03-
item.languageiso639-1en-
item.openairetypeThesis-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.grantfulltextopen-
Appears in Collections:Theses and dissertations (Applied Sciences)
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