Review on natural coumarin lead compounds for their pharmacological activity
Venugopala, Katharigatta Narayanaswamy
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Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.
Venugopala, K.N.; Rashmi, V. and Odhav, B. 2013. Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity. BioMed Research International, 2013.